Anlotib

About this medicine

Originator: Catequentinib by Chia-tai Tianqing Pharmaceutical Co., Ltd. · Manufacturer: Ziska Pharma. Indication & Dosage: Anlotib (Anlotinib), generic Catequentinib is a prescription medicine used to treat advanced non small cell lung cancer (NSCLC) who failed two lines of chemotherapy. Anlotinib is a methoxyquinoline-indole derivative and it is a novel small-molecule TKI, has multiple targets of action, which can effectively inhibit tyrosine kinase activity, block EGFR-mediated tumor cell signaling, suppress angiogenesis, and inhibit tumor cell growth, thus promoting tumor cell apoptosis. The National Medical Products Administration approved anlotinib monotherapy as a third-line treatment for patients with advanced NSCLC and additionally, a phase IIB randomized trial substantiated that anlotinib is associated with a significant longer median PFS in patients with advanced soft tissue sarcoma. Anlotib is manufactured by Ziska Pharmaceuticals Ltd. in Bangladesh. Anlotinib has to take orally once daily. Side Effects: The most common adverse reaction of Anlotinib are: hypertension (15.4%) , oral ulcers (7.7%) , hand–foot syndrome (7.7%) , bleeding (7.7%) , and fatigue (11.5%). And the adverse reactions related to temozolomide are: leukocyte decline (15.4%), anemia (3.8%), and liver function impairment (7.7%). The above information comes from the Internet. Please consult with doctor for medical advice.

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